Taking into account data from the literature referred to in this work, it seems that the interaction between the cells of the pathogen and enterocytes is prerequisite for the occurrence of the B. cereus-mediated diarrheal type of food poisoning. The adhesion of B. cereus to the epithelium allows them to colonize this environment and remain there for a sufficient amount of time in order to grow and achieve appropriately high count levels. It also allows them to produce enterotoxins in very close proximity to the epithelium. This situation prevents enterotoxins from being inactivated. Another factor which may play a role in the initial stage of food poisoning is likely a compound produced by epithelial cells which induces the germination process of B. cereus spores.