Indeed, MDA is frequently used as a biomarker of LPO because its facile reaction with 2-thiobarbituric acid (TBA)forms an intensely colored chromogen.
Although the relation-ships between the levels of MDA and various diseases have been investigated for several years [5], no reports have appeared previously discussing the variation in oxidative stress during microbial growth.
Monitoring the dynamic variations in MDA during microbial growth would require a sampling technique that could be used to continuously monitor dynamic changes in the levels of MDA with a certain temporal resolution.