Finally, analysis of biopsy specimens from the 33 long term survivors is interesting. There was no difference between abstinents and users, except for one patient with acute alcoholic hepatitis. We observed neither fibrosis nor cirrhosis. The length of the follow up cannot be the only argument put forward, as alcoholic cirrhosis recurrence 21 months after liver transplantation has been reported. Baddour et al found four of 23 patients developed cirrhosis, detected by liver biopsy performed from 177 to 711 days after liver transplantation. No relation between fibrosis and immunosuppressive drugs has been found.