3.3. Developmental toxicity and neurotoxicity
A continuous priority in public health has been the protection of children from adverse health effects of environmental toxicants, and the removal of lead from gasoline because of its developmental neurotoxicity can be seen as a main event of this endeavor. There is now recognition that children are not just little adults, but there exist child-specific factors that may render them more susceptible to environmental exposures; these include both toxicokinetic and toxicodynamic components, particularly at the level of the CNS [63]. In the past decade, a report from the National Academy of Sciences has highlighted the potential higher exposure of children to pesticides [64], and the Food Quality Protection Act indicates that in the risk assessment process, an additional safety factor should be included to ensure protection of children who are presumed to be more sensitive to toxicants' effects [65].