Material and Method
The present study was approved by Ethical
Committee of Bangkok Metropolitan Administration.
Inclusion criteria were children 15 years old or under,
diagnosed as nosocomial infection and culture from
clinical specimen grew bacteria. Nosocomial bacterial
infection was defined as identification of bacteria from
specimen with signs and symptoms of the site of infection,
occurring more than 48 hours after admission(1).
Bacterial isolates without signs and symptoms of the
suspected site of infection (bacterial colonization)
were excluded.
Bacterial isolates and susceptibility patterns
of pediatric patients with nosocomial bacterial infections
admitted at BMA Medical College and Vajira
Hospital between January 2000-December 2002 and
January 2003-December 2005 were reviewed and comparatively
analyzed. Antimicrobial susceptibility tests
were performed by the disk diffusion method as recommended
by the National Committee for Clinical Laboratory
Standards (NCCLS)(14).
Statistical analysis
Statistical analysis was performed by Stata
version 7.0. Categorical data was expressed as percent
and compared between the two groups by Chi-square
test. Continuous data were expressed as mean + SD
and compared between the two groups by student’s
t-test. A p-value < 0.05 was considered statistically
significant.
Results