4. Conclusions
IGT and PVA were blended with the NC powder to improve the
spin ability. The IGT/PVA ratio varied during the experiments and
the nanofibres with the best morphology were obtained at 20/80
IGT/PVA ratio in the presence of certain amount of NC. According
to the results obtained, the average size of nanofibres increased
with adding NC powder to the solution. The samples with 3%
of NC powder showed excellent bioactivity, biodegradation, and
mechanical property compared to the samples with lower amount
of NC powder. The obtained results in this research showed that
a pure IGT system could not directly be electrospun to yield
continuous and uniform nanofibres. To overcome the poor electrospinnability
of IGT solution, synthetic polymers such as PVA
solution were blended with IGT solution. Furthermore, the blend
nanofibres showed advancement in mechanical properties compared
to the pure electrospun PVA. The results of FTIR and XRD
indicated that there were strong interactions between NC and
PVA. Biocompatibility and bioactivity properties of IGT/PVA-3% NC
revealed that these nanofibres are suitable for wound healing and
can protect the wound surface from the infection as well as dehydration.