Clinical Course
The infants often have transient respiratory distress
at birth due to asphyxia or occasionally to
hyaline membrane disease. Such distress clears (or
is not present at all) and strikingly, the infants
almost always do well for several days up to over
a month; (in one of our cases onset of symptoms
did not occur until the forty-first day). The syndrome
can develop within hours of birth, however.
There is gradual onset of intermittent or continuous
cyanosis requiring continuous oxygen therapy,