The association between contact precautions and adverse events (such as diminished frequency and intensity of contact with healthcare workers, increased likelihood of medication errors, pressure sores, falls, depression and anxiety, and delays in hospital admission and discharge) is uncertain [38]. One randomized trial evaluating the impact of contact precautions on the incidence of adverse patient events noted a trend to fewer adverse events among patients on contact isolation precautions [37]. Other reports describe observational (and mostly retrospective) data and lack statistical power