Sparsely scattered necrotic cell debris, extravasated erythrocytes
(indicative of acute hemorrhage), and haemosiderin-laden
macrophages (indicative of chronic hemorrhage)were considered a
mild increase for each of these parameters. Focal dense accumulations
of these components in the wound tissue were considered
a moderate increase. Extensive tissue necrosis, massive hemorrhage
involving the surrounding tissue, and the presence of greater
than 30 haemosiderin-laden macrophages per 400× magnification
fields were considered a marked increase for each of these parameters,
respectively.
Slight separation of cells and collagen from one another in the
wound tissue by non-staining or poorly staining acellular material