After screening for inclusion and exclusion criteria, the patients included into the study were put to a pre-therapy PFT using Schiller SP1 Portable Spirometer, Germany. Patients were given clear instructions and demonstration of the PFT technique in a sitting position. Instructions given were as per the American Thoracic Society guidelines and were given 1 h prior to the procedure. Patients were allowed to practice for six to eight times during the training for PFT. Baseline data of PFT measures was collected before administration of therapy. Three efforts were allowed and the best of the three values was considered.