Numerous images showed secretory vesicles
packed with nascent VLDL just beneath the sinusoidal
surface of the hepatocytes (Fig. 13). VLDL
were also present among the microvilli of the space
of Disse. In all these locations, the VLDL in
experimental sections were heavily invested with
reaction product. The electron density of the walls
of the secretory vesicles was often greater than that
of other cytoplasmic membranes and corresponding
structures in control sections (Figs. 8, bottom,
and 13). This was also true of the plasma membrane
of the sinusoidal surface and the microvilli at
regions where particles were present in the space of
Disse (Fig. 13).