Lotus (Nelumbo nucifera) leaves, a traditional Chinese medicinal herb, are rich
in flavonoids. In an effort to thoroughly analyze their flavonoid components, macroporous
resin chromatography coupled with HPLC-MS/MS was employed to simultaneously enrich
and identify flavonoids from lotus leaves. Flavonoids extracted from lotus leaves were
selectively enriched in the macroporous resin column, eluted subsequently as fraction II,
and successively subjected to analysis with the HPLC-MS/MS and bioactivity assays.
Altogether, fourteen flavonoids were identified, four of which were identified from lotus
leaves for the first time, including quercetin 3-O-rhamnopyranosyl-(1→2)-glucopyranoside,
quercetin 3-O-arabinoside, diosmetin 7-O-hexose, and isorhamnetin 3-O-arabinopyranosyl-(
1→2)-glucopyranoside. Further bioactivity assays revealed that these flavonoids
from lotus leaves possess strong antioxidant activity, and demonstrate very good potential to
be explored as food supplements or even pharmaceutical products to improve human health
Lotus (Nelumbo nucifera) leaves, a traditional Chinese medicinal herb, are richin flavonoids. In an effort to thoroughly analyze their flavonoid components, macroporousresin chromatography coupled with HPLC-MS/MS was employed to simultaneously enrichand identify flavonoids from lotus leaves. Flavonoids extracted from lotus leaves wereselectively enriched in the macroporous resin column, eluted subsequently as fraction II,and successively subjected to analysis with the HPLC-MS/MS and bioactivity assays.Altogether, fourteen flavonoids were identified, four of which were identified from lotusleaves for the first time, including quercetin 3-O-rhamnopyranosyl-(1→2)-glucopyranoside,quercetin 3-O-arabinoside, diosmetin 7-O-hexose, and isorhamnetin 3-O-arabinopyranosyl-(1→2)-glucopyranoside. Further bioactivity assays revealed that these flavonoidsfrom lotus leaves possess strong antioxidant activity, and demonstrate very good potential tobe explored as food supplements or even pharmaceutical products to improve human health
การแปล กรุณารอสักครู่..
