MRSA was recognized as an important nosocomial infection in the U.S. in the late 1960s, and became endemic in human health care settings. The National Nosocomial Infections Surveillance System (NNIS) reports an increasing trend of MRSA. A 40% increase in resistance was noted in 1999 compared to the results of 1994-1998 data (NNIS, 2000). MRSA accounts for 52.3% of S. aureus nosocomial infections (NNIS, 2000). MRSA is now endemic in many hospitals, and is one of the leading causes of nosocomial pneumonia and surgical site infection and the second leading cause of nosocomial blood stream infections (Boyce et al., 1994).