Mediterranean diet did not vary by hormone-receptor subtype in
the European Prospective Investigation into Cancer and Nutrition
cohort (17). Whether hormone levels from endogenous or
exogenous sources, as reflected in menopausal status, HT use,
and body mass, modify the diet-cancer relation is not clear.
Whereas some studies have reported a reduced risk associated
with a healthy diet only among postmenopausal women (16, 24),
others have found a reduced risk only among premenopausal
women (11, 23). The Hormones and Diet in the Etiology of
Breast Cancer cohort found that the salad/vegetables dietary
pattern was inversely associated with breast cancer risk only among
women of normal weight, regardless of menopausal status (5).
We observed no statistically significant interactions between the
dietary patterns and menopausal status/HT use or BMI. Taken
together, our findings and much of the published literature
suggest that greater adherence to a healthy diet characterized by
greater consumption of plant-based items may reduce the risk of
some types of breast cancer
Mediterranean diet did not vary by hormone-receptor subtype inthe European Prospective Investigation into Cancer and Nutritioncohort (17). Whether hormone levels from endogenous orexogenous sources, as reflected in menopausal status, HT use,and body mass, modify the diet-cancer relation is not clear.Whereas some studies have reported a reduced risk associatedwith a healthy diet only among postmenopausal women (16, 24),others have found a reduced risk only among premenopausalwomen (11, 23). The Hormones and Diet in the Etiology ofBreast Cancer cohort found that the salad/vegetables dietarypattern was inversely associated with breast cancer risk only amongwomen of normal weight, regardless of menopausal status (5).We observed no statistically significant interactions between thedietary patterns and menopausal status/HT use or BMI. Takentogether, our findings and much of the published literaturesuggest that greater adherence to a healthy diet characterized bygreater consumption of plant-based items may reduce the risk ofsome types of breast cancer
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