This form of OA results from conditions that induce a change in the microenvironment of the cartilage. Such conditions include significant trauma, congenital joint abnormalities, metabolic defects (eg, Wilson disease), infections, diseases (eg, neuropathic), and disorders that alter the normal structure and function of cartilage (eg, Rheumatoid Arthritis, gout).
Secondary OA tends to appear in relatively young individuals aged approximately 45 or 50.