Three-dimensional structures of family GH12 cellulases have been obtained for one enzyme from Archea Pyrococcus furiosus DSM 3638 (GenBank Accession AAD54602.1), five bacterial enzymes namely from Bacillus licheniformis ATCC 14580/DSM13 [40], from Rhodothermus marinus[41], from Streptomyces lividans 1326 [42], from Streptomyces sp.