INTRODUCTION
Since the first report of livestock poisoning caused by cyanobacteria in
1878,1 incident of human and animal intoxication by cyanobacterial
blooms has occurred with increasing frequency, and the case has
become more serious since 1960.2 Many methods have been
developed to manage cyanobacterial blooms;3–5 however, it is
difficult to regulate the occurrence of cyanobacteria by the
conventional methods such as biomanipulation and algicides.6
Several studies have shown that actinomycetes and their metabolites
have great potential for controlling cyanobacterial blooms.7–13
Actinomycetes are the predominant producer of bioactive
compounds, and about 45% of the 22 500 bioactive compounds
from microorganisms are produced by actinomycetes.14 Streptomyces,
the largest antibiotic-producing genus,15 is the dominant group
of actinomycetes, and 75% of bioactive compounds from
actinomycetes are produced by Streptomyces.14 During a search for
anti-cyanobacterial microbes, strain JXJ 0135T exhibiting strong
anti-cyanobacterial activity was screened out. The main objective
of this study was to determine the taxonomic position of strain