Nucleic acids exist in all living creatures and function in encoding,
transmitting and expressing genetic information through their
specific sequence, or the order of nucleotides within the nucleic
acids. Therefore, detecting nucleic acids gives high sensitivity and
specificity in diagnosing particular diseases. As it is necessary to
obtain a large quantity of nucleic acids for the diagnosis, it is often
more useful to generate multiple copies of a target from a single
molecule of nucleic acid by amplification methods, as opposed to
the very time-consuming culture. This can accelerate the time for
nucleic acid diagnosis. However, nucleic acid-based detection
requires expensive instruments and reagents, extensively trained
technicians, and a long process time due to the complex analytical
procedures. The procedures are composed of multiple steps of
sample lysis to expose nucleic acids inside cells, purification of
lysate to extract only nucleic acids from cell components, amplifi-