Because infection is the greatest hazard of the postoperative period, nurses are continually on the alert for the usual manifestations of CSF infection, including elevated temperature, poor feeding, vomiting, decreased responsiveness, and seizure activity. There may be signs of local inflammation at the operative sites and along the shunt tract. Antibiotics are administered by the IV route as ordered, and the nurse may also need to assist with intraventricular instillation. The incision site is inspected for leakage, and any suspected drainage is tested for glucose, an indication of CSF.