Ultrasound imaging was the first effective soft tissue imaging modality used in diagnostic radiology as it provided tomographic views of the anatomy. After the introduction of ultrasound imaging, computed tomography (CT) and Magnetic Resonance Imaging (MRI) were introduced for disease diagnosis and management. Although CT and MRI are used extensively, ultrasound imaging provides unique advantages over CT and MRI with its ability for real-time imaging, its low cost, and small size allowing imaging at the patient’s bedside. Ultrasound imaging and therapy, as a major imaging and a promising treatment modality, have drawn the attention of numerous medical physicists and medical physics groups. A good model for ultrasound in medical physics programs was provided by the English, perhaps most strongly by Hill and his group at the Royal Marsden Hospital.