5 HT caused shivering and vasoconstriction and a
concomitant rise in core temperature while, nor epinephrine
and epinephrine lowered the normal resting temperature
in cat and attenuated the 5 HT induced hyperthermia.31
The balance between the modulatory 5 HT and nor
epinephrine inputs may be responsible for short and long
term thermoregulatory adaptive modifications of the
shivering threshold.32 Dopamine has also been found to
induce hypothermia to a lesser extent in unanaesthetised
monkey when injected into hypothalamus.