Flavivirus infections are a significant public health
problem. The two medically important and closely-related
members of Flaviviridae family include dengue virus (DV)
and Japanese encephalitis virus (JEV). In the most areas of
Asia, DV and JEV co-circulate[1]. In the Indian subcontinent
and Southeast Asia, they are important causes of human
disease and mortality. JEV and DV exhibit significant
serological cross-reactivity, which can complicate
assessment of the relative burdens of each in co-endemic
areas and also make the serological diagnosis of both the
diseases difficult[2-4]. DV (types 1, 2, 3 and 4) typically
cause dengue fever (DF) and dengue haemorrhagic fever/