every race in the world has practisd the ancient art of medicinal plants
the earliest record of the medicinal usage of plant
the chinaese pharmacopoeia was publish in approximately 3000BC
herbal medicine has also been an integral part of thai culture for a long period of time not only used as drugs but also applied as food and constituent in cosmetics
although the interest in medicinal plants has sometime declined study of natural product in recent years have been gaining much attention because of their biological activity
the search for bioactive components from plant as a source of lead compounds in drug development is therefore an important endeavor in phytochemistry
several isolated compound were identified as novel compounds and a number of known compounds were reisolate and proved to possess biological activity
however the isolation of biologically activity organic compounds in several plant has some limitations
in some case pure compounds separated from plants were not enough for further investigation and commercial utilization
thus syntheses of the compounds which are of structures based on biological activity compounds isolated from plant are worth concern