Disinfection is essential part of any emergency response to support disease control activities such as quarantine of affected aquaculture establishments and stamping-out procedures. The conditions associated with an emergency response require different approaches for disinfection to those used in routine biosecurity. These conditions include a high level of diseaserisk (due to the significance of the disease), high pathogen loading, potential high volumes of infected aquatic animals and waste, large areas requiring disinfection and large volumes of contaminated water. Planning should consider these circumstances, incorporate an evaluation of risks and include methods for monitoring efficacy.