However, in other
studies, the effect of nanoparticle size does not appear to be significant. For instance, the uptake of
silver nanoparticles and quantum dots into macrophages induces the expression of inflammatory
mediators such as TNF-α, MIP-2, and IL-1β independent of size (22, 28). Additional work is still
required before researchers fully understand the fate and toxicity of internalized nanoparticles