Most of the available data from this technique has
been published in the neonatal field where it is increasingly
used [4,5]. HFNC is considered to have a
number of advantages over conventional oxygen delivery
systems, resulting in better physiological effects.
Recently, its use with critically ill adults has been
dramatically rising. It has been applied to a variety of
patients with diverse underlying diseases. While many
of the studies have been clinical trials, no results from
reliable, large, controlled clinical trials have yet been
published. In the literature, the technique has also
been called mini-CPAP (continuous positive airway
pressure), transnasal insufflation, nasal high flow, nasal
high-flow ventilation, high-flow therapy, and high-flow
nasal cannula oxygen therapy. Here, we use the term
HFNC throughout the text, in which we summarize
the physiological effects of HFNC and then review the
clinical trials.
Most of the available data from this technique hasbeen published in the neonatal field where it is increasinglyused [4,5]. HFNC is considered to have anumber of advantages over conventional oxygen deliverysystems, resulting in better physiological effects.Recently, its use with critically ill adults has beendramatically rising. It has been applied to a variety ofpatients with diverse underlying diseases. While manyof the studies have been clinical trials, no results fromreliable, large, controlled clinical trials have yet beenpublished. In the literature, the technique has alsobeen called mini-CPAP (continuous positive airwaypressure), transnasal insufflation, nasal high flow, nasalhigh-flow ventilation, high-flow therapy, and high-flownasal cannula oxygen therapy. Here, we use the termHFNC throughout the text, in which we summarizethe physiological effects of HFNC and then review theclinical trials.
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