This was mainly attributable to insufficient consumption of fatty fish [20], reduced nuts, seeds, and whole-grain cereals in alimentation [21] and a progressive preferential use of safflower oil, poor in n-3 PUFA. Importantly, marine fish and especially fatty ones are the most important source of n-3 PUFA in the Occident. Aside from marine alga and newly engineered oils and supplements [20, 22], marine fish represent the only natural edible source of long-chain (LC) n-3 PUFA eicosapentaenoic and docosahexaenoic acids(EPA and DHA), the most biologically active n-3 PUFA [23]. In Occidentalized countries, fish consumption is very variable and globally low [24, 25].