The therapeutic potential of isolated compounds or extracts from the medicinal mushroom P. linteus has been clearly demonstrated in rigorous scientific studies. In addition, the therapeutic effects of P. linteus extract were independently described in case reports. Collectively, these studies justify the use of dietary supplements containing P. linteus extract for the alternative treatment of cancer. One such dietary supplement is Breast-Mate®, whose major component is an extract from P. linteus which has exhibited antiproliferative, anti-invasive and anti-angiogenic activities against highly invasive human breast cancer cells.