Quinic acid (Fig. 4i) was also identified in all antigiardial T. ferdianadiana fruit extracts. Recent studies have reported that substituted quinic acid compounds block leucyl-transfer RNA (tRNA) synthase activity in G. lamblia (Zhang et al., 2012). Aminoacyl-tRNA synthases are essential for translationof the genetic code byattaching the correct amino acid to each tRNA. Thus, blockage of leucyl-tRNA synthase activity would result in ineffective Leu-tRNA production and thus the inhibition of protein synthesis.We were unable to find reports of nonsubstituted quinic acid having the same activity