Due to the lack of experimental solubility data of caffeine in
the CO2 + EL and CO2 + EAC supercritical solvents, the solubility (Y*)
was estimated as the slope of a theoretical linear behavior of the
OEC between t = 0 and t = 14 min (Table 4). For comparison,the estimated
caffeine solubility in pure CO2 was 0.029% mass, which is
quite in agreement with the experimental solubility measured at
343K and 28.1 MPa (0.023% mass) [35]. These estimated solubilities
presume that, as in the case of the solubility of caffeine in
the liquid solvents [30,31], the solubility of caffeine in CO2 with
ethyl lactate cosolvent is higher than in the case of ethanol or ethyl
acetate cosolvents.
Due to the lack of experimental solubility data of caffeine inthe CO2 + EL and CO2 + EAC supercritical solvents, the solubility (Y*)was estimated as the slope of a theoretical linear behavior of theOEC between t = 0 and t = 14 min (Table 4). For comparison,the estimatedcaffeine solubility in pure CO2 was 0.029% mass, which isquite in agreement with the experimental solubility measured at343K and 28.1 MPa (0.023% mass) [35]. These estimated solubilitiespresume that, as in the case of the solubility of caffeine inthe liquid solvents [30,31], the solubility of caffeine in CO2 withethyl lactate cosolvent is higher than in the case of ethanol or ethylacetate cosolvents.
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