Solid-lipid particles can be produced using the similar methods
to those used for creating conventional emulsions.
However,
the lipid components are carefully chosen so that all or part of
the lipid in the emulsion droplets solidifies after processing and
cooling.
A key component to solid-lipid particle production is to
homogenize the lipid and aqueous phases at a temperature that
is higher than the melting point of the lipids (Helgason et al.,
2008; Schubert and Muller-Goymann, 2005). If the temperature
is too low, solid lipid components will not be homogenized
and may damage the processing equipment (McClements et al.,
2007).
After processing, cooling of the formed particles is also
important to form a solid lipid emulsion droplet with the correct
lipid crystal configuration (Fig. 5).