This study indicates that Curcuminoids are well tolerated at the dose level of 1500
mg/d in patients with knee OA. The results of this study showed marked improvement in all the
assessed efficacy measures therefore it clearly favored the efficacy of Curcuminoids in
alleviating the symptoms and improving the care of patients with OA. Thus it can be said that
Curcuminoids represent an effective and safe alternative treatment for OA.
The positive result in this trial provide a base for future larger-scale phase III trials to explore if
Curcuminoids can be used in the therapeutic regimen of patients suffering from knee OA.