sponge collected in Davao, was partitioned successively with hexane and chloroform, and the active chloroform extract (150 mg) was chromatographed on a C18 flash column from 100% deionized water (0.5% TFA) to 100% methanol
sponge collected in Davao,was partitioned successively with hexane and chloroform,and the active chloroform extract (150 mg) was chromatographedon a C18 flash column from 100% deionizedwater (0.5% TFA) to 100% methanol