Actinomycete strain SA198, isolated from a Saharan soil sample of Algeria, exhibited antimicrobial activity
against Gram-positive and Gram-negative bacteria, and phytopathogenic and toxinogenic fungi. The morphological and chemotaxonomic characteristics of the strain were consistent with those of the genus
Saccharothrix. Analysis of the 16S rRNA gene sequence of strain SA198 showed a similarity level ranging
between 97.2 and 98.8% within Saccharothrix species, S. australiensis being the most closely related. Two
new active products were isolated by reverse HPLC using a C18 column. The ultraviolet–visible (UV–VIS),
were new bioactive compounds. The minimum inhibitory concentrations of these antibiotics
infrared (IR), mass, and 1Hand 14C nuclear magnetic resonance (NMR) spectra showed that these products showed a
strong activity against fungi and moderate activities against Gram-positive and Gram-negative bacteria
Actinomycete strain SA198, isolated from a Saharan soil sample of Algeria, exhibited antimicrobial activity
against Gram-positive and Gram-negative bacteria, and phytopathogenic and toxinogenic fungi. The morphological and chemotaxonomic characteristics of the strain were consistent with those of the genus
Saccharothrix. Analysis of the 16S rRNA gene sequence of strain SA198 showed a similarity level ranging
between 97.2 and 98.8% within Saccharothrix species, S. australiensis being the most closely related. Two
new active products were isolated by reverse HPLC using a C18 column. The ultraviolet–visible (UV–VIS),
were new bioactive compounds. The minimum inhibitory concentrations of these antibiotics
infrared (IR), mass, and 1Hand 14C nuclear magnetic resonance (NMR) spectra showed that these products showed a
strong activity against fungi and moderate activities against Gram-positive and Gram-negative bacteria
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