The performance of four traditional fully porous particle supports with particle sizes ranging between 3.0 and 3.5m
(ACE3, Gemini NX, Hypersil Gold and XBridge) and three superficially porous columns with particle sizes of 2.6–2.7m (Kinetex, HALO and Poroshell 120), all with a C18 stationary phase, was evaluated
at pH= 4.5 using G1 as test compound.