reduction of severe neonatal complications (OR
0.29, 95% CI 0.09–1.00) (25). Women with known
migraine or recurrent headaches should not take NO,
as it causes headache in as many as two-thirds of all
patients taking it (17). Other potential side effects include
myalgia, contact dermatitis from the adhesive
in the patch, and hypotension and/or orthostatic
dysregulation at the start of treatment. No fetal side
effects or teratological effects have been described.
In a follow-up study, children born after nitroglycerin
tocolysis were found to be neu rologically
normal 18 months later (26).