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Of concern is the effect of total fat, especially saturated fat, on insulin sensitivity in persons with diabetes. Epidemiologic data and clinical trials have reported that long-term higher total fat intake results in greater whole-body insulin resistance.34,35 Although not as well studied in persons with diabetes, reducing saturated fat has been shown to improve insulin sensitivity.36,37 The impact of long-term intake of saturated fatty acids on insulin resistance is important because as people with diabetes decrease their intake of carbohydrate, they increase their fat intake, especially of saturated fat.
33Of concern is the effect of total fat, especially saturated fat, on insulin sensitivity in persons with diabetes. Epidemiologic data and clinical trials have reported that long-term higher total fat intake results in greater whole-body insulin resistance.34,35 Although not as well studied in persons with diabetes, reducing saturated fat has been shown to improve insulin sensitivity.36,37 The impact of long-term intake of saturated fatty acids on insulin resistance is important because as people with diabetes decrease their intake of carbohydrate, they increase their fat intake, especially of saturated fat.
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