In the medical profession, the communication between doctors and patients will be easy when they are come from the same place or same culture. On the other hand, it will be difficult to communicate if they are come from the different culture even if they use the same language. The different behaviors of each other are occurring from the different of cultural and tradition that make the different expression. Finally, the important of the study is the obvious and interprets in communication to prevent the mistake in cross-cultural communication.