As previously mentioned, S. maltophilia is classified as
multi-drug-resistant bacteria and is characterized by a high
intrinsic capacity to resist a wide range of antimicrobial
molecules. Its intrinsic resistance is particularly due to the
presence of broad-spectrum efflux pumps, enzymes such as L1
metallo-b-lactamase, L2 Ambler class A b-lactamase and
AAC(60)-Iz and APH(30)-IIa aminoglycoside-modifying enzymes
Various studies have also revealed the capacities of
clinical strains to develop antibiotic resistance mechanisms
due to mutation or acquisition of mobile elements . S.
maltophilia, as a multi-drug-resistant opportunistic pathogen,
resists antibiotics and biocides like hypochlorite cleaners,
triclosan, SDS and antiseptics containing quaternary ammonium
compounds