antitumor antibody bound to gold attaches to
cancer cells, the gold absorbs laser light and
allows selective tumor photothermolysis (12).
(a)
(b)
Fig. 1. Dermatoscopy and confocal microscope represent dermatological
devices largely used for early detection of sub-clinical melanoma.
Nanoparticles are used in these new technologies. Clinical case of
melanoma that was not clinically recognized: dermatoscopy (a) and
confocal imaging (b) reveal suspicious features. (a) Multicomponent
pattern shows colors and pigment network asymmetrically distributed.
Pigment dots are randomly located and differ in size. (b) Epidermal
architecture; melanocytic proliferation; highly refractile
structures with dendritic branching, consistent with atypical melanocytes;
nesting of bright cells with atypical morphological features;
and loss of cell-to-cell demarcation.
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Saraceno et al.
Finally, dendrimers are the first, large
man-made molecules with precise, nano-sized
composition and well-defined three-dimensional
shapes. Dendrimers have been used as
delivery systems for chemotherapeutics/
antineoplastics (29)