Out of 22 500 biologically active compounds obtained from microbes, 45% are from actinomycetes, 38% from fungi and 17% from other bacteria[11]. Over 5 000 antibiotics have been identified from the culture of Gram positive, Gram negative bacteria and filamentous fungi[12]. Species of Streptomyces, account for more than 70% of the total antibiotic production and Micromonospora was less than one-tenth as many as Streptomyces[13]. Twenty seven actinomycetes were isolated from Mount Everest region soil samples and reported to have antibacterial activity against at least one tested bacteria among the two Gram positive and nine Gram negative bacteria[14]. Narendra Kumar et al. isolated 117 antibiotic producing actinomycetes from non agricultural wasteland alkaline soils and compost rich garden soil in which most of the isolates inhibits Gram negative bacterial growth[15]. Four potential antibacterial actinomycetes were isolated from the aquatic environment[16]. Valli et al. isolated 21 potential actinomycetes from marine environment and reported that all the isolates were promising against at least one tested organisms[17]. Kalyani et al. isolated 20 species from marine soil samples in which three showed significant antimicrobial activity against Staphylococcus aureus and Escherichia coli (E. coli