Rosuvastatin calcium (ROS) is chemically, bis[(E)-7[4-(4-fluorophenyl)-6-isopropyl- 2-[methyl (methylsulphonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid] calcium salt . It belongs to a class of drugs called statins, which are employed to lower hypercholesterolemia and related conditions and to prevent cardiovascular diseases. It increases the number of hepatic low-density lipoprotein receptors involved in the catabolism
of LDL and also inhibits hepatic synthesis of very low-density lipoprotein . Fenofibrate (FEN) is 2-[4-(4-chlorobenzoyl)
phenoxy]-2-methyl-propanoic acid, 1-methylethyl ester. It is indicated for the treatment of hypercholesterolemia and mixed dyslipidemia