The placebo-adjusted
mean plasma glucose was also significantly decreased in all
groups except for the 100 mg group (all P0.001 except for
the 100 mg dose, P=0.613). These results were reproduced
2 weeks after the treatment period ended. Greater fluctuations
in fasting plasma glucose were seen with biweekly and
monthly doses, whereas once-weekly doses of albiglutide
produced more consistent results.14