phagocytic activity %, and histopatho logical alterations in gills (hyper mucus, congestion, swelling , edema , hyperplasia, haemolymph cell infiltration as well as thickened and enlarged gill chambers & lamellar sinuses), hepatopancreas (dissolving of the hepatocytes, haemolysis, haemocytic infiltration in the interstitial sinuses, thickening and ruptures of the basal laminae) and skeletal muscles (degeneration in muscles with infiltration and aggregations of hemocytes between them and focal areas of necrosis)