In a previous study, Takahashi et al. reported that C18:0 and total saturated fatty acids, as well as LA, AA, and -6 unsaturated fatty acids, were lower in women than in men in elderly subjects (average age: 78 years) [33]. Furthermore, they suggested that -6 fatty acid levels in serum decreased with age, particularly in women. On the other hand, in a study of individuals of
all ages (0–90 years), Holman et al. found that, while total serum lipid unsaturation was significantly higher in men than in women, there were no significant differences in fatty acid concentrations between men and women [34]. Furthermore, the activity of - 6-desaturase was shown to be reduced in elderly subjects in a healthy Tunisian population. The enzyme -6-desaturase modifies the fatty acid structure by introducing a double bond at the-6 position [3,35–37]. LA is converted to GLA through the action of- 6-desaturase, and GLA is elongated to form DGLA. DGLA can then be
In a previous study, Takahashi et al. reported that C18:0 and total saturated fatty acids, as well as LA, AA, and -6 unsaturated fatty acids, were lower in women than in men in elderly subjects (average age: 78 years) [33]. Furthermore, they suggested that -6 fatty acid levels in serum decreased with age, particularly in women. On the other hand, in a study of individuals ofall ages (0–90 years), Holman et al. found that, while total serum lipid unsaturation was significantly higher in men than in women, there were no significant differences in fatty acid concentrations between men and women [34]. Furthermore, the activity of - 6-desaturase was shown to be reduced in elderly subjects in a healthy Tunisian population. The enzyme -6-desaturase modifies the fatty acid structure by introducing a double bond at the-6 position [3,35–37]. LA is converted to GLA through the action of- 6-desaturase, and GLA is elongated to form DGLA. DGLA can then be
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