2.4. Event-related potential measurement
Event-related potential (N100 and P300 amplitude and latencies)
of all subjects were measured using an “oddball paradigm”
(Kennedy et al., 2003). N100 and P300 amplitude and latencies
were elicited with a standard auditory oddball paradigm.
Frequent and target tones were presented binaurally through
headphones. Participants were instructed to listen for and
count infrequent target tones (650 Hz, 60 dB, 200 ms), which
occurred randomly amongst 82–90 frequent non-target tones
(1 kHz, 60 dB, 200 ms). Inter-stimulus intervals varied randomly
between 1250 and 3000 ms. The latency range in which the N100
and P300 maximum amplitudes and latencies were determined
was between 65–135 and 280–375 ms, respectively. However,
any peaks outside this range were measured manually, with
preliminary visual checking of all peaks prior to measurement
2.4. Event-related potential measurementEvent-related potential (N100 and P300 amplitude and latencies)of all subjects were measured using an “oddball paradigm”(Kennedy et al., 2003). N100 and P300 amplitude and latencieswere elicited with a standard auditory oddball paradigm.Frequent and target tones were presented binaurally throughheadphones. Participants were instructed to listen for andcount infrequent target tones (650 Hz, 60 dB, 200 ms), whichoccurred randomly amongst 82–90 frequent non-target tones(1 kHz, 60 dB, 200 ms). Inter-stimulus intervals varied randomlybetween 1250 and 3000 ms. The latency range in which the N100and P300 maximum amplitudes and latencies were determinedwas between 65–135 and 280–375 ms, respectively. However,any peaks outside this range were measured manually, withpreliminary visual checking of all peaks prior to measurement
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