Loop diuretics, especially furosemide, are widely used
in various conditions. The bioavailability of furosemide
differs between oral and intravenous therapy. The threshold
and ceiling doses of furosemide differ according to
the clinical condition. Furosemide also has several side
effects, especially in CKD patients. To maximize the efficiency
of furosemide, a solid understanding of its bioavailability
and dose adjustment kinetics associated with each
route of administration is necessary