Major points:
- Excess CRH inhibits TSH.
- Excess glucocorticoids (e.g. cortisol) inhibit conversion of the less active T4 to the more active T3.
- Excess high cortisol can result in high output of rT3 which inhibits T3.
Common Acronyms:
HPA Axis = Hypothalamic Pituitary Adrenal Axis HPT Axis: Hypothalamic Pituitary Thyroid Axis
CRH = Corticotrophic Releasing Hormone ACTH = Adrenocorticotrophic Hormone
TRH = Thyroid Releasing Hormone TSH = Thyroid Stimulating Hormone rT3 = Reverse T3