Dose-dependent human oral absorption of curcuminoids upon
consumption of hard gelatin capsules of 1000 mg, 250 mg and
100 mg doses of FTC have shown significant (p < 0.001) absorption
of curcuminoids into the blood stream as compared
to standard curcumin (DTC) at equivalent doses. Since FTC contains
only 4.2% of total curcumin content as measured by
curcumin, DMC and BDMC levels, the above doses of FTC were
found to contain only 42, 10.5 and 4.2 mg respectively of total
curcuminoids.The equivalent doses of standard curcumin (DTC)
were 42, 11.0 and 4.4 mg respectively, since the total curcumin
content of DTC used in the present study was 95.1%. Although
a dose dependence in absorption of curcuminoids was
observed (as measured by the various pharmacokinetic pa-