During my study the accumulation of trace elements between
smoker and non smoker revealed significant increase
of cadimium levels in smoker patients and significant
decrease of chromium while there was no significant
differences in iron concentration between them.
The cadmium concentration in the range 1 - 2 μg do occur
in differed reference population and arise from differences
in environmental exposure as well as other biological
factors. So cadmium levels in human eye patients
a significantly increase in comparison to healthy controls.
Chromium from food and beverages is poorly absorbed
and toxicity of chromium is mainly due to chromium that
can be absorbed by the respiratory tract and also to certain
extent by the intact skin. Smoker get exposed to significantly
higher cadmium levels than non smoker severe
damage to lungs may occur through breathing higher
levels of cadmium. The potential ocular toxicity of these
heavy metals and their possible role in eye disease requires further study.